منابع مشابه
Cretinism revisited.
Endemic cretinism includes two syndromes: a more common neurological disorder with brain damage, deaf mutism, squint and spastic paresis of the legs and a less common syndrome of severe hypothyroidism, growth retardation and less severe mental defect. Both conditions are due to dietary iodine deficiency and can be prevented by correction of iodine deficiency before pregnancy. Endemic cretinism ...
متن کاملExperimental Cretinism
Findly (1908) and Mellanby (1919) clearly demonstrated that rickets occurred in young animals fed on a diet containing an insufficient amount of certain substances now known as the “antirachitic vitamine.” As a result of this, the British Medical Research Committee announced that rickets is a deficiency disease due to a lack in the diet of an anti-rachitic factor. For literature up to 1923, cov...
متن کاملNon-endemic goitrous cretinism.
Enlargement of the thyroid gland is an unusual finding in cretins outside endemic goitrous areas. Wilkins, Clayton and Bertirong (1954), reviewing published cases of non-endemic goitrous cretinism, collected reports of 32 cases and described a further four cases of their own. Other cases have been reported by Rienhoff (1940) and Smallpeice (1949). The hypothyroidism in these cases is of variabl...
متن کاملMorphological Studies in Experimental Cretinism
In summarizing the findings of this paper it may be said that degenerative changes have been noted in practically every parenchymatous organ. Among these the most striking has been that of serous imbibition by the most active cells of these organs. In regard to the changes in the glands of internal secretion, the findings corroborate the statements of Cushing in regard to hypophysectomy, that r...
متن کاملPituitary cretinism in two sisters.
Two sisters with cretinism are reported. Each showed low levels of serum triiodothyronine, thyroxine, and thyroid-stimulating hormone (TSH). In the elder sister, serum TSH did not increase after administration of thyrotropin-releasing hormone. We conclude that cretinism in these 2 sisters was due to TSH deficiency. This is the second report of 'familial' pituitary cretinism (TSH-deficient conge...
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ژورنال
عنوان ژورنال: The Boston Medical and Surgical Journal
سال: 1901
ISSN: 0096-6762,1533-4406
DOI: 10.1056/nejm190110101451502